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Oct 5, 2015

Webinar on Exosome RNA for Biomarker Development and Clinical Applications of Exosome Biomarkers


Johan Skog, CSO of Exosome Diagnostics, Will Discuss Exosome RNA for Biomarker Development and Clinical Applications of Exosome Biomarkers in Free Webinar on Tuesday, October 6, 11 AM EDT

Sun, 10/04/2015 - 07:25 — bioquicknews

A free, live-broadcast webinar on exosome RNA biomarkers will be presented on Tuesday, October 6, 2015, beginning at 11 am EDT. In a 90-minute presentation, industry expert Dr. Johan Skog, Chief Scientific Officer and Founding Scientist at Exosome Diagnostics, will discuss the exosome composition, different sources of RNA in biofluids, and approaches to isolate them. Following this overview, he will speak about clinical applications of exosome biomarkers. To learn more about this free event, and to register for it, please visit: http://xtalks.com/Exosome-RNA-for-Biomarker-Development.ashx. Discovery and validation of biomarkers has traditionally required the use of tissue for analysis of RNA, DNA or protein. This has been especially true for RNA-based biomarkers, because RNase degradation of free RNA makes translation of tissue-based biomarkers into blood based tests highly problematic. However, the discovery that exosomes found in biofluids contain stable, disease-specific RNA, represents a potential paradigm shift for biomarker discovery and development. Exosome RNA can be used to monitor tumor-derived mutations in biofluids, but can also be used to monitor RNA levels reflective of different signaling pathways (including mRNA, miRNA, lncRNA and other types of RNA). In addition, exosome RNA can be used to monitor cell activities resulting in fusions and RNA splice variants that cannot be measured on circulating free tumor DNA. Dr. Johan Skog is a renowned, well-published thought leader in exosome science, having pioneered breakthrough discoveries about exosomes and other microvesicles and their vital role as cell messengers and disease proliferators. While at Massachusetts General Hospital/Harvard Medical School, Dr. Skog discovered that tumor-derived mutations can be detected in exosome RNA from serum and other biofluids, findings which were published in Nature Cell Biology in 2008.

Additionally, he demonstrated that exosomes serve to deliver messages to other cells, inducing message that induce changes favorable to the proliferation of cancer.

At Exosome Diagnostics, Dr. Skog continues to pioneer critical advancements in diagnostics and to expand the field of exosome biology.

Dr. Skog’s research background includes virology, gene therapy, brain tumors, RNA, and biomarker discovery, and he is an inventor on several patents. Dr. Skog earned his Master of Biomedical Sciences and Doctorate at Umeå University, Sweden

This highly informative and timely webinar is being produced by Xtalks, which is powered by Honeycomb Worldwide Inc., and is a leading provider of educational webinars to the global Life Sciences community.

Every year thousands of industry practitioners (from pharmaceutical & biotech companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content.

Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com. For information about hosting a webinar visit http://xtalks.com/sponsorship.ashx.

[Register for webinar "Exosome RNA for Biiomarker Development] [Exosome Diagnostics] [Xtalks]

(Source: Directly adapted from http://www.bioquicknews.com/node/2994)

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